Antibody microarrays encompass different platforms, sizes, and species, and may provide either a qualitative or quantitative readout. But one thing they all have in common is the ability to generate highly multiplexed data.
Here we explain how antibody microchips are used and how they can be used for research. You can also check out Boster Bio featured products to know more about antibodies.
Antibody microchips cover a wide range of targets and are often designed based on protein class, signaling pathway, or research area. The primary use of antibody microchips is to assess the expression of protein biomarkers in samples.
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With the help of microprocessing of the targeted proteome or antibody, it is possible to look for markers of protein biomarkers associated with different stages of the disease, or to assess protein activation and cell signaling, Antibody microchips are also used to quickly identify pathogens with similar clinical features.
Researchers at the Smorodintsev Influenza Research Institute in St. Petersburg, Russia, recently developed an antibody microchip that can distinguish six common viruses that cause upper respiratory disease. This shows a slightly lower detection limit than that observed in classical ELISA.
In addition to testing multiple targets simultaneously, antibody microchips offer many additional advantages. The main advantage of antibody microchips is that they minimize the need for sample volume.
Researchers using antibody microchips can gain a broad view of protein expression in similar sample volumes with single-target assays such as ELISA. This can be especially important for species or samples where volume or protein content is limited.